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Lastly, the study conclusions could not apply to frequent e-cigarette users who do not engage with e-cigarette advocacy groups and online boards. Some adults use e-cigarettes once they wish to stop smoking tobacco cigarettes. While a latest report found e-cigarettes are "much less toxic" than cigarettes, most individuals who use e-cigarettes do not quit using cigarettes. Taken collectively, there isn't any doubt tobacco cigarette smoke has extreme cardiovascular side effects leading to endothelial dysfunction, increased oxidative stress, and increased cardiovascular morbidity and mortality. There is also proof that e-cigarette vapour is less toxic than tobacco smoke. Nevertheless, acute e-cigarette smoking increases blood strain, causes endothelial dysfunction and increases vascular and cerebral oxidative stress.

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